PFIZER
WHEN WAS IT APPROVED? December 11, 2020
WHO CAN GET IT? Anyone 16 or older
DOSAGE: 2 doses, given 21 days apart
HOW DOES IT WORK? Uses messenger RNA to deliver a tiny bit of genetic code from the virus to ‘teach’ the body to make a protein that provoke antibody production
HOW EFFECTIVE IS IT…
AFTER 2 DOSES: 95% effective at preventing illness; 100% effective at preventing COVID-19 death; 87% effective at preventing hospitalization
AFTER FIRST DOSE: (not recommended) ~46% effective at preventing infection seven to 20 days later; 57% effective against against symptomatic illness; 72% effective at preventing death; 74% effective against hospitalization; 62% effective against severe illness (based on real-world data from Israel)
AGAINST VARIANTS FROM…
UK – B117: No significant impact
South Africa – B1351: 10% less effective; still protective
Brazil – P1: 10.4-fold weaker antibodies; still protective
MODERNA
WHEN WAS IT APPROVED? December 18, 2020
WHO CAN GET IT? Anyone 18 or older
DOSAGE: 2 doses, given 28 days apart
HOW DOES IT WORK? Uses messenger RNA to deliver a tiny bit of genetic code from the virus to ‘teach’ the body to make a protein that provoke antibody production
HOW EFFECTIVE IS IT…
AFTER 2 DOSES: 94% effective at preventing illness; 100% effective at preventing COVID-19 death; 89% effective at preventing hospitalization
AFTER FIRST DOSE: (not recommended) ~80% effective, based on trial data
AGAINST VARIANTS FROM…
UK – B117: No significant impact
South Africa – B1351: 10% less effective; still protective
Brazil – P1: More data needed
JOHNSON & JOHNSON
WHEN WAS IT APPROVED? February 27, 2021
WHO CAN GET IT? Anyone 18 or older
DOSAGE: 1 dose
HOW DOES IT WORK? Uses a harmless, inactivated cold virus to carry piece of spike protein into body to teach it to fight SARS-CoV-2
HOW EFFECTIVE IS IT…
AFTER SINGLE DOSE: 72% worldwide; 86% in the US
AGAINST VARIANTS FROM…
UK – B117: No significant impact
South Africa – B1351: 64% effective
Brazil – P1: 85% effective