Tiny plastic particles have been discovered in unborn baby rats, the first time microplastics have been seen to cross the placenta in live mammals.
Researchers found the particles had travelled from the body of the the mother, across the placenta and then into the vital organs of the foetus.
The study also revealed that nanoparticles of polystyrene were able to reach the foetus just 90 minutes after the mother was exposed.
Just one day later, the impact of the plastic led to exposed foetuses being seven per cent smaller than expected.
Scientists do not yet know if the findings also apply to human pregnancy but the findings are a cause for concern.
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Tiny ‘nanoparticles’ of plastic that drift around every surface and substance of our world can pass from a mother’s body to her fetus’s brain, heart or lungs, a new study in rats suggests
Plastics are made of long-chained polymers which shed and degrade over time into smaller fragments known as microplastics.
These fibres, less than 5mm in size, , are thought to pose a risk to animal and human health but the exact extend of their hazards remains unknown.
Microplastics have been spotted in the most desolate parts of the world, including the Alps, Antarctica and the ‘death zone’ of Mt Everest.
Nanoplastics however are around 1,000 times smaller than microplastics and even less is known about their impact on human and animal health.
Researchers from Rutgers University tried to learn more by creating spherical pieces of polystyrene which measured just 20 nanometres across.
In reality, nanoplastics are not perfectly round, but are irregularly shaped and more closely resemble a flake than a ball, which may alter their ability to infiltrate human systems, but more research is needed to understand this mechanism, scientists say.
The spherical nanoplastics were attached to a fluorescent particle so the scientists could see how far they had reached after being given to rats in a lab.
‘Twenty-four hours later on gestation day 20, maternal and fetal tissues were evaluated using fluorescent optical imaging,’ the researchers write in their study, published in the journal Particle and Fibre Toxicology.
Microscope images show microplastics in the livers, lungs, kidneys, hearts and brains of rate fetuses whose mothers were exposed to the nanoparticles (white)
During this critical time, the developing rat fetuses whose mothers were exposed to microplastics (red) weighed seven percent less than healthy control rats (blue)
Analysis of the animals revealed the foetuses of exposed mothers were seven per cent lighter than was expected. The placenta was also eight per cent lighter than control animals.
Microscope images found nanopolystyrene particles in the lung, heart, and spleen of the mother.
Polystyrene nanoparticles were also seen in the placenta, liver, lungs, heart, kidney, and brain of the foetus ‘suggesting maternal lung-to-fetal tissue nanoparticle translocation in late stage pregnancy’, the researchers write.
Previous studies have found an average person eats, drinks and inhales up to 142 tiny pieces of plastic a day, according to a 2019 University of Victoria study.
This equates to about 74,000 a particles a year, or about a credit card of plastic a week.
Plastics are thought to damage health by physically interfering with systems and tissues, such as by restricting nutritional uptake.
But they can also carry harmful chemicals which, at high enough doses, may also be harmful to human health.
Phthalates and bisphenols, for example, have been found to alter hormone levels and negatively affect fertility.
Babies have been found to be exposed to microplastic shards from their milk bottles as particles are released from their vessels via the sterilisation process.
And scientists had already discovered that these plastics can cross the typically effective blood-brain barrier.
‘This study answers some questions and opens up other questions,’ Professor Phoebe Stapleton, lead author of the study from Rutgers University, told The Guardian.
‘We now know the particles are able to cross into the fetal compartment, but we don’t know if they’re lodged there or if the body just walls them off, so there’s no additional toxicity.’